Cardiovascular disease and breast cancer are the two leading causes of death in the United States for women. Both are associated with inflammation.
Strategies to reduce inflammation may be an effective treatment option to reduce cardiovascular disease and breast cancer.
Chronic inflammation leads to the release of inflammatory cytokines. These inflammatory cytokines contribute to cellular damage, which leads to disease onset or progression. Chronic diseases such as atherosclerosis, osteoporosis, and diabetes all have an inflammatory component.
There are medications to reduce inflammation, such as steroids and non-steroidal anti-inflammatory drugs (NSAIDS), but all medication comes with side effects and these are no exception. Potential side effects include nausea, constipation, diarrhea, headache, dizziness, weight gain, increase blood pressure, and immune suppression among others.
Alternate treatment options are desirable for treating inflammation, such as dietary interventions. Improving dietary quality with emphasis on specific anti-inflammatory nutrients is a safe strategy for reducing inflammation and disease risk.
Foods high in added sugar that should be avoided or limited include soft drinks, energy drinks, sports drinks, cakes, pastries, donuts, fruit drinks, ice cream, pudding, cookies, candy, pie, and cobblers.
This is a guest post from Jonny Bowden.
Jonny Bowden, PhD, CNS, (aka “The Rogue Nutritionist”) is a nationally known expert on weight loss, nutrition and health. He is a board-certified nutritionist with a master’s degree in psychology and the best-selling author of 14 books on health, healing, food and longevity, including three best-sellers, “The 150 Healthiest Foods on Earth”, the award-winning “Living Low Carb” and his latest book, co-written with cardiologist Stephen Sinatra and featured on the Dr. Oz Show, “The Great Cholesterol Myth”.
Nutritionist debunks some old wives’ tales so that you can enjoy your meals again
Let’s talk fat. Specifically, saturated fat. If you’ve banished red meats and egg yolks from your diet for health reasons, there’s reason to rejoice. “I think the notion that saturated fat and cholesterol are the demons in the diet is 100 percent wrong,” says Dr. Jonny Bowden PhD, CNS, a nationally known expert on weight loss, nutrition and health. “When you look at the data, it’s very clear: Most of what we’ve been told about saturated fat and cholesterol is simply not so.”
Bowden, a board-certified nutritionist and author of 14 books including The Great Cholesterol Myth co-authored with cardiologist Stephen Sinatra, explains that, “I’m out to rehabilitate the reputation of saturated fat, a perfectly healthy fat that we collectively demonized when we wrongly believed it lead to heart disease. Recent research has shown that there’s no connection between saturated fat in the diet and the incidence of heart disease. Instead of saturated fat and cholesterol, most leading edge experts are now looking at inflammation as a prime mover in the development of heart disease.
“The irony is that the foods we were taught are good for us – breads, cereals, pasta, rice, potatoes – are the very ones that are killing us. Our bodies convert these foods to sugar almost instantly. Sugar raises insulin, which causes inflammation, which is the fundamental cause of heart disease.”
Consuming a low cholesterol diet is not necessarily the best treatment plan for lowering cholesterol levels and reducing your risk for heart disease.
Why? Well, it depends on which of your total cholesterol particles is elevated. For example, if LDL cholesterol is high, it’s best to focus on reducing your intake of saturated fat. If triglycerides are elevated you want to reduce your sugar and alcohol intake for the most impact. Knowing which of your cholesterol particles is elevated will allow you to implement a more effective treatment plan.
Then you also have the other component – inflammation. Cholesterol by itself does not necessarily lead to heart disease. It’s a process that begins with inflammation resulting in the oxidation of cholesterol particles. So, you also want to incorporate a diet rich in “anti-inflammatory foods”.
How to Follow an Anti-Inflammatory Diet
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Do you take statin medication? If so, when did your doctor recommend you being statins? Was it when your lab results found your LDL cholesterol levels to be elevated?
LDL cholesterol has been the measure used to determine when lipid lowering therapy is needed…and statins are often the therapy started.
Research is beginning to question if LDL is the best measure for knowing if cholesterol treatment is warranted to reduce heart disease risk.
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For quite awhile now, I’ve been encouraging you to look at more than just your standard cholesterol panel to assess your risk for heart disease. I’m going to share the findings of an expert panel that supports this need.
In the Journal of Clinical Lipidology a panel of specialists concluded that patients considered at intermediate risk for heart disease be tested for C-reactive protein. It’s likely this applies to a majority of the U.S. population since overweight and obesity is rampant. Family history, diet, exercise, and tobacco use also factor into determining if you are at intermediate risk.
Just evaluating total cholesterol, LDL cholesterol, and HDL cholesterol does not work well for predicting heart attack and stroke risk, especially for patients with metabolic syndrome or diabetes. It’s even more difficult to evaluate risk if a patient is using cholesterol lowering statin medications.
C-Reactive Protein
C-Reactive protein is a marker for inflammation and is associated with plaque build up in blood vessel walls. The plaque build up in coronary arteries leads to narrow arteries, which can cause chest pain. If these arteries rupture you are dealing with a heart attack or stroke.
If you are to successfully lose weight you will likely focus on eating fewer calories and increasing your activity to burn more calories. It’s important that you also address inflammation on your journey to lose weight.
Research on mice has shown a “switch” controlling inflammation in the hypothalamus (region of the brain that regulates energy) becomes “flipped on” in response to high fat diets. It also shows that “overnutrition” (i.e. eating too much) turns on this inflammatory switch.
An increased level of inflammation leads our cells to become resistant to insulin and leptin.
Insulin plays a messenger role in that it tells cells it is time to take in glucose (sugar). If cells become resistant to insulin, they ignore the message that it is time to take in more glucose, glucose is converted to fatty acids, and is stored by our fat cells. If insulin resistance is persistent, eventually the fat cells will no longer respond and increased levels of fatty acids will remain in circulation.
Leptin is a hormone that triggers satiety. This is your body’s way of telling you you’ve had enough to eat. When production of leptin is hindered, we do not feel satisfied and tend to eat more.
As inflammation causes the cells to ignore the messages of insulin and leptin, you are more likely to consume more calories (because you still feel hungry) and potentially store increased levels of fat due to the increased level of circulating fatty acids.