Heart Disease and the B Vitamin Choline

A proposed link between the B vitamin choline and coronary artery disease is being explored. The relationship between choline and coronary artery disease (CAD) may involve the accumulation of homocysteine and the effect these concentrated homocysteine levels have on endothelial cells (inner layer of blood vessels).

Several studies indicate that homocysteine levels are a key contributor and primary risk factor for CAD. While on the flip side, several studies have shown no decreased CAD risk with a reduction in homocysteine levels.

So, the importance of choline in reducing the risk of coronary artery disease is debatable. Regardless, choline plays important roles in metabolism and normal cell function, so it’s worth knowing a little about this B vitamin.

Functions of Choline

Fat metabolism
Facilitates movement and coordination
Component of all cell membranes

Causes of Choline Deficiency

Alcohol
High intake of sugar
Nicotine
Folic acid deficiency

Symptoms of Choline Deficiency

High blood pressure
High cholesterol
Nervous system disorders

Food Sources of Choline

Beef
Egg Yolks
Oats
Brewer’s Yeast
Chicken
Nuts
Peanut Butter

How much choline

The recommended choline intake ranges between 400-500 mg per day. Do not supplement more than 3 grams daily. Choline is a water-soluble vitamin which means it leaves the body fairly quickly. If you supplement choline it’s wise to break the dose in half and supplement twice a day. For example, this would mean 200-250 mg twice a day.

All the best,
Lisa Nelson RD
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