A proposed link between the B vitamin choline and coronary artery disease is being explored. The relationship between choline and coronary artery disease (CAD) may involve the accumulation of homocysteine and the effect these concentrated homocysteine levels have on endothelial cells (inner layer of blood vessels).
Several studies indicate that homocysteine levels are a key contributor and primary risk factor for CAD. While on the flip side, several studies have shown no decreased CAD risk with a reduction in homocysteine levels.
So, the importance of choline in reducing the risk of coronary artery disease is debatable. Regardless, choline plays important roles in metabolism and normal cell function, so it’s worth knowing a little about this B vitamin.